Cholesterol – Triglycerides

Bioelectromagnetics. 2007 Dec;28(8):608-14.

Alimentary hyperlipemia of rabbits is affected by exposure to low-intensity pulsed magnetic fields.

Luo E, Shen G, Xie K, Wu X, Xu Q, Lu L, Jing X.

Department of Military Medical Equipment & Metrology, Faculty of Biomedical Engineering, The Fourth Military Medical University, Xi’an, China. tocooper@hotmail.com

Abstract

An experimental study was carried out in rabbits to investigate the effects of exposing rabbits to low-intensity pulsed magnetic fields (PMFs) on alimentary hyperlipemia. Thirty female white big ear rabbits were randomly divided into three groups. The normal group was fed with a standard chow diet and the other two groups (hyperlipid and magnetic) were fed with the chow diet supplemented with cholesterol, yolk powder and lard. The magnetic group was exposed to 15 Hz pulsed magnetic fields. After 8 weeks, levels of blood lipid and indices of hemorheology were examined. In addition, histomorphologic changes of hepatic and myocardial tissues were compared across the groups respectively. Compared with the hyperlipid group, hemorheology indices of the magnetic group reduced significantly from 12.80% to 38.05% (P < 0.01) indicating lower blood viscosity. Similarly, compared with the hyperlipid group, the levels of total cholesterol and triglycerides in the magnetic group decreased 40.52% and 52.42% (P < 0.01). On the contrary, high density lipoprotein (HDL) value obviously increased 66.67% (P < 0.01). Furthermore, compared with the control group, the values of triglycerides and HDL of the magnetic group did not show statistical differences (P > 0.05). The deposit of fatty material on the inner lining of thoracic aorta wall of the magnetic group was significantly lighter than that of the hyperlipid group. Numerous aggregation of lipoids emerged among myocardial myofibrils in the hyperlipid group, while no notable change was found in both the magnetic and control group. The results indicate that low-intensity PMFs could be helpful for the treatment of alimentary hyperlipemia.

Lipids Health Dis. 2007 Nov 16;6:31.

Effects of whole body exposure to extremely low frequency electromagnetic fields (ELF-EMF) on serum and liver lipid levels, in the rat.

Torres-Duran PV, Ferreira-Hermosillo A, Juarez-Oropeza MA, Elias-Viñas D, Verdugo-Diaz L.

Department of Physiology, School of Medicine, UNAM, P.O. Box 70250, Mexico, D.F. 04510, Mexico. pavito@correo.unam.mx

Abstract

BACKGROUND: [corrected] The effects of extremely low-frequency electromagnetic fields (ELF-EMF) on the blood serum and liver lipid concentrations of male Wistar rats were assessed.

METHODS: Animals were exposed to a single stimulation (2 h) of ELF-EMF (60 Hz, 2.4 mT) or sham-stimulated and thereafter sacrificed at different times (24, 48 or 96 h after beginning the exposure).

RESULTS: Blood lipids showed, at 48 h stimulated animals, a significant increase of cholesterol associated to high density lipoproteins (HDL-C) than those observed at any other studied time. Free fatty acid serum presented at 24 h significant increases in comparison with control group. The other serum lipids, triacylglycerols and total cholesterol did not show differences between groups, at any time evaluated. No statistical differences were shown on total lipids of the liver but total cholesterol was elevated at 24 h with a significant decrease at 96 h (p = 0.026). The ELF-EMF stimulation increased the liver content of lipoperoxides at 24 h.

CONCLUSION: Single exposures to ELF-EMF increases the serum values of HDL-C, the liver content of lipoperoxides and decreases total cholesterol of the liver. The mechanisms for the effects of ELF-EMF on lipid metabolism are not well understand yet, but could be associated to the nitric oxide synthase EMF-stimulation.

Panminerva Med. 1998 Dec;40(4):276-9

Effect of pulsed magnetic fields on triglyceride and cholesterol levels in plasma of rats.

Bellossi A, Pouvreau-Quilien V, Rocher C, Ruelloux M.

Laboratoire de Biophysique Faculte de Medecine, Rennes, France.

BACKGROUND: Liver is a crucial organ in metabolism. For instance liver is the main source of circulating lipoproteins.

METHODS: In this paper cholesterol and triglyceride plasma levels were measured in male rats previously exposed to pulsed magnetic fields (PMF) used in therapy. Rats underwent a one-hour exposure to a 6 mT 12 Hz PMF.

RESULTS: Twenty-four hours after the end of the exposure to the PMF the rats’ livers were heavier, cholesterol and triglyceride plasma levels decreased. All these variations were significantly different according to a variance ratio test as was a rebound in triglyceride level 48 hours after the end of the exposure. Normal values were observed 48 and 96 hours after the end of exposure respectively for cholesterol and triglycerides.

CONCLUSIONS: These alterations may be due to a reversible accumulation of either triglycerides or of their precursors in liver following acute exposure to a 12 Hz PMF.

Biofizika. 1985 Mar-Apr;30(2):313-6.

Correction of lipid metabolism in rats with limited mobility by an alternating magnetic field of infra-low frequency.

[Article in Russian]

Temur’iants NA, Evstaf’eva EV, Makeev VB.

Abstract

The effect of changing magnetic field at the frequency of 8 Hz and intensity at 4.1 A/M on rats lipid metabolism state in the exposition of continuous hypokinesia was investigated. It was found that changing magnetic field of such parameters greatly restricted the development of hyperlipidemia of rats with a low level of mobile activity.

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